Phosphocholine as a pattern recognition ligand for CD36

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Phosphocholine as a pattern recognition ligand for CD36.

We have previously shown that CD36 recognizes oxidation products of phospholipids on oxidized LDL (OxLDL) such as 1-palmitoyl-2-(5'-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC). The current study was designed to examine whether the phosphocholine (PC) headgroup in POVPC constitutes an obligatory binding target for CD36. To examine the contribution of PC in the binding of POVPC to CD36, we u...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 2005

ISSN: 0022-2275

DOI: 10.1194/jlr.m400496-jlr200